Xenotransplantation—the process of transplanting organs between different species—is seen as a solution to the limitation of organ shortage among human patients.

Researchers have been exploring strategies to minimize organ rejection, including modifying the organ donor’s genes and developing immune-suppressing drugs for recipients. Researchers from NIH’s National Heart, Lung, and Blood Institute (NHLBI) have been working for years to develop procedures for transplanting hearts from pigs to primates. Pigs share characteristics with humans that make them a promising species for xenotransplantation. The team’s latest study, led by Dr. Muhammad M. Mohiuddin, was published on April 5, 2016, in Nature Communications.


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